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AlphaGenome is a new AI model that predicts how single DNA variants impact gene regulation.

It processes very long DNA sequences (up to one million base-pairs) at single-base resolution.

The model predicts multiple molecular properties, including gene expression, splicing, and chromatin accessibility.

Apptainer simplifies creating and running containers for portability and reproducibility

It provides secure, unprivileged execution preventing privilege escalation

Containers can be encrypted and integrated with secret management systems

Snow emulates Motorola 680x0-based classic Macintosh computers with a graphical user interface.

It performs hardware-level emulation without ROM patching and includes extensive debugging features.

Supports Macintosh 128K, 512K, Plus, SE, Classic, and II models.

Initial AI code reviewer was too noisy, producing many low-value comments and false positives

Requiring the AI to log explicit reasoning improved traceability and reduced arbitrary findings

Simplifying the toolset to only essential components increased review precision

Journavx (suzetrigine) is the first FDA-approved non-opioid analgesic for treating acute post-surgery pain.

It works by selectively blocking NaV1.8 sodium channels on peripheral nociceptors, preventing pain signals from reaching the brain.

Because it does not enter the central nervous system, it avoids opioid-related euphoria, addiction, and respiratory depression.

Microsoft allegedly blocked an ICC employee’s mailbox in compliance with US sanctions, highlighting potential risks of forced service cutoffs.

Although the probability of a sanction-driven Microsoft service outage is low, it is non-zero due to unpredictable government actions.

Organizations heavily depend on Microsoft products—Office 365, Azure, Exchange, Active Directory—making outages severely disruptive.

The PNG specification has been updated for the first time in over 20 years to add new features and keep the format competitive.

Proper HDR support is introduced, enabling high dynamic range color with minimal overhead.

APNG (animated PNG) is officially recognized in the specification.

The National Archives at College Park holds permanent federal records including civilian textual records, Army WWI and Navy WWII unit records, still pictures, electronic records, cartographic and architectural holdings, motion pictures, sound and video records, JFK assassination records, and Berlin Documents Center microfilm.

Highlights from the holdings include photographs and graphic works as well as significant textual records.

The facility is located at 8601 Adelphi Road, College Park, MD, with truck deliveries at 3301 Metzerott Road.

X11 can support DPI and fractional scaling by using XrandR to obtain each monitor’s physical dimensions and resolution

By computing the size in pixels from the monitor’s millimeter width and resolution, you can render elements at a consistent physical size

An example drawing a two-inch circle with OpenGL updates its pixel radius based on the monitor it is on

Judge William Alsup ruled that Anthropic’s use of published books to train its AI models qualifies as fair use.

This is the first federal court decision supporting a fair use defense for AI companies using copyrighted materials in large language model training.

The ruling represents a setback for authors, artists, and publishers suing AI firms over copyright infringement.